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Application of Kamagra is contraindicated to patients with hypersensitivity to the active substance or to any other component of the drug. Due to the effect on the exchange of nitrogen oxide/cGMP, sildenafil enhances the hypotensive effect of nitrates when they are used once or for a long time, therefore its simultaneous use with nitrogen oxide donators, organic nitrates, or nitrites in any form is permanently or periodically contraindicated.
Morphine is used for the management of chronic, moderate to severe pain.
Opioids, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.