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Flunitrazepam 2mg, 30pieces

Management of flunitrazepam intoxication is largely supportive. Neurologic impairment, amnesia, and respiratory depression, which may begin as early as 30 minutes after ingestion, generally last for 8 to 12 hours and are dose-related.132 Support of the patient with a jeopardized airway is indicated

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Flunitrazepam has acquired a reputation for toxicity, abuse potential [1] and associated forensic problems , including being implicated in sexual assault (“date rape”) . It has been withdrawn from general availability in various countries, including the USA, Australia, and New Zealand, and it is considered to be a narcotic in various European countries. It has a rapid onset of action but a long half-life. The earlier recommended hypnotic dose (1–2 mg) is excessive, and like some other benzodiazepines, such as triazolam, flunitrazepam is safer in a smaller dose . Like triazolam, it has been associated with nocturnal binge eating. Although its outpatient use in individuals who are susceptible to abuse is hazardous, intravenous flunitrazepam is useful for alcohol.Flunitrazepam, marketed as Rohypnol, is a potent benzodiazepine that is marketed legally in South America, although its sale in the United States and Canada has been restricted. It is 10 times as potent as diazepam, and shares amnestic properties with other benzodiazepines.126 Its potency and ability to produce amnesia has led to its misuse in facilitating sexual assault, giving it the reputation of being a “date rape drug.”127,128 It is available under a variety of street names including “rookie,” “circle,” “rope,” and “forget-me,” as a 1- or 2-mg scored pill that may be colored to obscure its identity. The pills are inexpensive, and thus thought of as a “cheap high.” They are imported illegally through the mail, and are acquired over the Internet from offshore sources. Although benzodiazepines may be detected by urine screen, flunitrazepam is generally taken at a dose below the detection limits of most assays.129

At low doses, flunitrazepam is an anxiolytic, muscle relaxant, and sedative-hypnotic. At higher doses, behavioral inhibition, amnesia, and unconsciousness occur, as may respiratory depression. Its effects are potentiated by the concurrent use of alcohol. Disinhibition may lead to motor vehicle accidents, other trauma, violent behavior, or sexual assault,130 and flunitrazepam has been implicated in the occurrence of violent crime.131 Fatal intoxication has been reported with the concurrent use of alcohol; rarely, death associated solely with the ingestion of flunitrazepam may occur.52

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